Worst Pills
atorvastatin (LIPITOR)

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include drug profiles where your selected drug is a primary subject of discussion

Disease and Drug Family Information

Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion
  • Elevated Cholesterol Levels [hide all summaries]
    The evidence for treatment, especially with cholesterol-lowering drugs, is much weaker for people who have not yet had the cardiovascular disease described above, known as primary prevention. This is especially so for those people who do not have more than one of the following risk factors: hypertension, diabetes, smoking, obesity, or a close family history of premature heart attacks or strokes.

Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Drugs That Cause Sun-Related Skin Reactions [hide all summaries]
    (July 2016)
    Summer is a terrific time for healthy outdoor activities, such as walking, hiking, biking and swim¬ming. But for an unlucky few, certain medications can lead to adverse skin reactions following exposure to the sun. Find out whether you are at risk and how to protect yourself.
  • More on Overprescribing Statins [hide all summaries]
    (March 2015)
    The most recently issued prescribing guidelines for cholesterol-lowering statin drugs were partly based on a new patient risk calculator that significantly overestimates patients’ risk of developing cardiovascular disease. Learn how this overestimation will lead to overprescribing of statin drugs to patients who will not benefit from using them.
  • New Cholesterol Treatment Guidelines Recommend Statins for More Patients [hide all summaries]
    (November 2014)
    One year ago, the American College of Cardiology and the American Heart Association released controversial new guidelines on treating high cholesterol. Get Public Citizen’s Health Research Group’s independent take on these new guidelines.
  • Statins for Primary Prevention: Risks Without Benefits [hide all summaries]
    (June 2013)
    For people who have had heart attacks, strokes and other cardiovascular diseases, statins can prevent further damage. But for primary prevention — in people without such disease — a number of articles raise serious questions about whether the risks of statins outweigh the benefits.
  • Updates: Pain, High Cholesterol and ADHD Drugs [hide all summaries]
    (June 2013)
    These updates provide new information that has become available since we published our last articles regarding these three categories of drugs.
  • Statins Frequently Cause Fatigue, Reduce Energy Levels [hide all summaries]
    (November 2012)
    Find out about the latest evidence that statins such as LIPITOR, LESCOL, ALTOPREV, MEVACOR, LIVALO, PRAVACHOL, CRESTOR and ZOCOR can cause fatigue and reduced energy levels, especially in women. The authors concluded that "These effects, germane to quality of life, merit consideration when prescribing or contemplating use of statins, particularly in groups without expected net morbidity/mortality benefit."
  • New Study on the Effectiveness of Statin Use in Women [hide all summaries]
    (October 2012)
    A recent study challenges the assumption that men and women with pre-existing cardiovascular disease benefit equally from the use of statins to prevent subsequent death or strokes.
  • Pfizer Succeeds at Slowing Loss of LIPITOR Sales After Patent Expires [hide all summaries]
    (July 2012)
    We discuss how Pfizer, after its patent on the billions-a-year-selling LIPITOR went off patent, used desperate means to delay giving patients options for much less expensive generic versions of the drug, marketed as atorvastatin.
  • Update on Grapefruit Juice-Drug Interactions [hide all summaries]
    (July 2012)
    This article updates and expands our earlier list of drugs that can have harmful interactions with grapefruit juice. The list now includes 82 different drugs.
  • Fenofibric Acid (TRILIPIX) May Not Lower Heart Attack/Stroke Risk [hide all summaries]
    (February 2012)
    Over 15.2 million prescriptions were filled in 2010 for the brand-name or generic versions of two essentially identical drugs (fenofibrate [TRICOR] and fenofibric acid [TRILIPIX]) that clearly do not add any benefits to taking statin drugs alone but add to the risks.
  • Pitavastatin (LIVALO): 8th Cholesterol-Lowering Statin Marketed in the U.S. [hide all summaries]
    (December 2010)
    Find out why you should not use the newest entry into the crowded statin market.
  • Fatal Drug Interactions With Simvastatin (ZOCOR) [hide all summaries]
    (December 2010)
    Find out how simvastatin (ZOCOR) can interact with another widely used drug to greatly increase the chance of life-threatening muscle damage that can lead to kidney damage.
  • Muscle Damage from Interactions Between Statins and Other Commonly Prescribed Drugs [hide all summaries]
    (July 2009)
    The article lists 38 prescription drugs that can harmfully interact with statin drugs. The article also advises that No matter what statin you are taking and regardless of any interacting drugs, you should notify your prescriber immediately if you develop muscle pain, weakness or a darkening of your urine. .
  • Colchicine Interactions with Other Drugs Can Be Life-Threatening [hide all summaries]
    (December 2008)
    This article lists 27 drugs that can have life-threatening interactions with the widely-used gout drug, colchicine, resulting in dangerously elevated levels of colchicine. Too much colchicine in the body leads to toxicity such as fever, vomiting, diarrhea, abdominal pain and muscle pains. Even worse, it can impair the bone marrow’s ability to make red and white blood cells, causing severe anemia and dangerously low numbers of white blood cells. When the number of white blood cells is reduced, your body may have difficulty fighting infections. Most people who have died from colchicine toxicity have had bone marrow toxicity or had preexisting kidney problems. Every patient on colchicine — whether on other drugs or not — should be alert for evidence of colchicine toxicity as described above.
  • Nightmares Associated with Atorvastatin (LIPITOR) [hide all summaries]
    (June 2006)
    Assume that any new symptom you develop after starting a new drug may be caused by the drug. If you develop a new symptom after starting atorvastatin or other statins (such as nightmares), report it to your doctor. The drug may be responsible.
  • The Cholesterol-Lowering Statin Drugs and Memory Loss [hide all summaries]
    (December 2005)
    In the October 2005 issue of the Canadian Adverse Reaction Newsletter, 19 case reports of memory loss or impairment associated with the use of a cholesterol-lowering statin drug were analyzed. If you are taking a statin drug and you notice memory problems, talk to your doctor about stopping the drug or reducing the dose.
  • Cholesterol-Lowering Statin Drugs and the Dietary Supplement Coenzyme Q10 [hide all summaries]
    (June 2005)
    You should not use coenzyme Q10 in an attempt to prevent or treat the adverse reactions associated with the use of the cholesterol lowering statin drugs.
  • The Cholesterol Lowering Statin Drugs — Not All Have Proven Health Benefits [hide all summaries]
    (March 2005)
    If you must use a statin drug to control your cholesterol, you should use one that has an FDA health benefit claim in its professional product labeling. (chart with these statins listed in the article)
  • Publicity about Recent Studies on the Cholesterol-lowering Statin Drugs: Misinterpretations [hide all summaries]
    (April 2004)
    There has been an extraordinary amount of news attention focused on recent studies concerning statins and heart disease, presented at the American College of Cardiology meetings in March and, in one case, published in the April 8, 2004 New England Journal of Medicine.This article discusses several specific ways in which industry-spun news coverage has misrepresented the facts about this issue.
  • Grapefruit Juice and Prescription Drugs: Some Dangerous Interactions [hide all summaries]
    (February 2004)
    The January 5th issue of the Medical Letter, a widely respected source of independent information about pharmaceuticals and dietary supplements, has a review of the increasingly researched problem of the interaction between grapefruit juice and many prescription and over-the-counter drugs. Like most interactions between chemicals in the body, this one involves the impairment, by grapefruit juice, of the body’s ability to metabolize many drugs, leading to higher than expected — and sometimes dangerous — levels of these drugs.This article lists the drugs.
  • Drug Induced Psychiatric Symptoms [hide all summaries]
    (October 2002)
    This is the first of a two part series on drug induced psychiatric symptoms that is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Regular readers of Worst Pills, Best Pills News will recognize The Medical Letter as a reference source written for physicians and pharmacists that we often use because of its reputation as an objective and independent source of drug information. The article lists the drugs and their psychiatric adverse effects.
  • Grapefruit Juice and Drug Interactions [hide all summaries]
    (June 2002)
    Grapefruit juice can interact with a number of therapeutically important drugs that could lead to the possibility of toxicity. These drugs are listed in the article.
  • FDA Safety Office Recommends Warning About Liver Failure With The Cholesterol Lowering “Statin” Drugs [hide all summaries]
    (January 2001)
    The Food and Drug Administration’s (FDA) Office of Postmarketing Drug Risk Assessment (OPDRA) recommended in a memorandum dated May 1, 2000, that liver failure be included as an adverse reaction in the professional product labeling, or “package insert” for the family of cholesterol-lowering drugs known as “statins.” The statins now being marketed in the U.S. are .....

Additional Information from Public Citizen

Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion

SHOW secondary search results for atorvastatin (LIPITOR)

Copyright © 2018 Public Citizen's Health Research Group. All rights reserved. https://www.worstpills.org/